MetasTx, LLC
February 10, 2025
Royale
Oncology
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MetasTx is working to block metastases of cancer cells from solid tumors including prostate, breast and skin by early detection and blockade of mesenchymal-to-epithelial transition (EMT). Creating novel drug focused on inhibiting P21-activated kinase (PAK 1) and companion diagnostic to detect activation of EMT. Initial target - 2 million men on active surveillance for prostate cancer.
Market Opportunity
$11.5 billion US drug market,
Mortality rates unchanged over the past 2 decades despite 35 drugs available.
Platform focus – Inhibit EMT
Target PAK1 to create First-In-Class drug to inhibit metastases.
Personalized and aggressive treatment intervention when needed.
Avoid unnecessary prostatectomies.
MetasTx Strengths:
1. Science Foundation – 35 published articles
2. Demonstrated capabilities for AI Drug and Biomarker Discovery
3. Efficient business strategy / Laser focus on exit by Acquisition
4. Extraordinary Leadership Team
Seeking lead for preferred equity Round of $2.5 M.
Speakers